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The main goal in Bacterial Takeover is to destroy as many planets as possible.
Attacking a planet uses up all [[Resources#Bacteria|bacteria]], and [[ColoniesResources#Nanobots|coloniesnanobots]], and resets [[Resources#NanobotsColonies|nanobotscolonies]] and resets bacteria [[Upgrades|upgrades]]. Destroying planets unlocks new upgrades and features, such as [[Research#Colony Irradiation|colony irradiation]] or [[Research#Nanobot Production|nanobot production]].
A planet counts as destroyed if its remaining population has been reduced to 0. Killing a percentage of a planet's population earns gene strands and there is no limit to how many times the player can attack one planet to destroy it.