*purchasing [[Diamonds#Premium Purchases| '''premium bonuses''']]

Most The player unlocks new bacteria upgrades can only by purchasing more colonies. After purchase, Bacteria upgrades cannot be bought once, but some are '''iterative'''sold or disabled. Iterative An option to buy all Bacteria upgrades usually become available is unlocked after the player has bought 200 of one colony type. Afterwards, they can be purchased once per 25 new coloniesdestroying [[Lableilara]].

The Most upgrades can only be bought once, but some are '''iterative'''. Iterative upgrades usually become available after the player unlocks new bacteria upgrades by purchasing more colonieshas bought 200 of one colony type. After purchaseAfterward, Bacteria upgrades cannot they can be sold or disabledpurchased once per 25 new colonies.

The ''Buy all For [[BPS]] colonies, there is also a second tier of iterative upgrades'' option , which becomes available per every 1000 colonies owned and provides a 500000% increase for the production of that colony. Currently, there is only one iterative bpc upgrade and it is unlocked after the player has destroyed obtaining 200 [[Colonies#Bacteria Guns|'''[[Lableilara]]Bacteria guns''']] and it can be purchased again after each 25 new Bacteria guns.

=Gene Strand Skill Point Upgrades=[[Gene StrandsFile:Skill point upgrades.png|Gene Strandthumb|right|200px|Skill tree]][[Skill Points|Skill point]] upgrades enable and increase the [[BPS#idle BPS|'''idle BPS bonus''']], [[Tapping Combo|'''tapping combo bonus''']], as well as provide various multipliers to total [[BPC]] and increase the production of different [[Colonies|'''colonies''']].

Gene Strand upgrades remain after planet attacksTo purchase an upgrade, but are lost upon entering it's necessary to purchase the prerequisite upgrade and have a '''[[Black Hole]]'''sufficient number of skill points.

==Gene Strand Bonus vsSkill point upgrades remain after planet attacks, but are lost upon entering a '''[[Black Hole]]'''. Gene Strand Upgrades=={{gs vs gs upgrades}}

=Upgrades Adding Bacteria from BPS to BPCEffect=Some regular and Gene Strand upgrades Upgrades can have a variety of effects, the simplest of which increase the total [[BPCBPS]] by a percentage of your total , while others may enable new [[Game Mechanics|game mechanics]], such as [[BPSconversion]] or [[Tapping Combo]]. They do not decrease your total BPS.

The effectiveness ==Upgrades Increasing Colony BPS==Many of these [[Upgrades#Bacteria Upgrades|Bacteria upgrades is determined by:*their base effect; ]] and*the number of destroyed [[PlanetsSkill Points|planetsskill point upgrades]]only increase the production of one colony by a certain percentage.

The base effect of such upgrades is not displayed in the upgrade descriptionmultiplicative. For regular upgradesexample, if you have an upgrade that increases the base effect usually is 1BPS of Petri Dish by 200% and an upgrade that increases Petri Dish BPS by 300%, but [[Toxic bullets]], for example, has a base effect then the total production of 5Petri Dish is increased by 600%. The final effect of the particular upgrade is calculated according to the formula:

<code>effect = base effect / PlanetsDestroyed=Upgrades Adding Bacteria from BPS to BPC=={{Upgrades Adding Bacteria from BPS to BPC}} '''²Main page:''' </code>[[BPS conversion]]

<!--===Gene Strand Upgrades===

*[[List of Tapping Combo Upgrades|Tapping Combo Upgrades]]--> =Version History={{version history table}} {{version history row|v = 1.34.0|changes = Added skill point system. [[List of All Gene Strand Upgrades| Gene Strand upgrades]] are replaced by a skill tree}} {{version history row|v = 1.19.0|changes = Reduced the effect of '''Germ banks''' upgrade from 10% to 3%}} {{version history row|v = 1.8.0|changes = New Gene Strand upgrades:*Subaquatic pandemic*Herald of plague*Space guilds}} {{version history row|v = 1.6.2|changes = Balancing:*Reduced Andromeda Strain idle BPS effect from 1000% to 10%*Total idle BPS effect from Gene Strand upgrades and [[Evolved Bacteria]] now is multiplied}} {{version history row|v = 1.6.0|changes = New Gene Strand upgrades:*Andromeda strain*After Earth}} {{version history row|v = 1.5.0|changes = New Gene Strand upgrades:*Rot influx*Cheap dirt*Mutant farmers}}|}[[Category:Upgrades]]