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The main goal in Bacterial Takeover is to destroy as many planets as possible.
Attacking a planet uses up all [[Resources#Bacteria|'''Bacteria''']] and [[Resources#Nanobots|'''Nanobots''']], and resets [[Colonies|'''colonies''']] and [[Upgrades|'''bacteria Bacteria upgrades''']]. Destroying planets unlocks new upgrades and features, such as [[Research#Colony Irradiation|Colony irradiation]] or [[Research#Nanobot Production|Nanobot production]].
After entering a '''[[Black Hole]]''', the player enters an alternate timeline where none of the planets have been destroyed. The planets in the alternate timeline have the same stats and defenses, but can unlock different features. For example, destroying the fifth planet after the first Black Hole unlocks [[Research#Bacteria Irradiation|'''Bacteria irradiation''']].