Upgrades increase the production of colonies, provide various multipliers to BPS, BPC, and unlock new game features.
Other ways of unlocking new features and boosting production include:
- equipping Evolved Bacteria
- researching the Dark Matter Institute technologies
- purchasing premium bonuses
- collecting Gene Strands
- completing certain achievements
Contents
Bacteria Upgrades
Bacteria upgrades give various multipliers to global BPS, BPC, as well as increase the production of different colonies.
Most upgrades can only be bought once, but some are iterative. Iterative upgrades usually become available after the player has bought 200 of one colony type. Afterwards, they can be purchased once per 25 new colonies.
The player unlocks new bacteria upgrades by purchasing more colonies. After purchase, Bacteria upgrades cannot be sold or disabled.
The Buy all upgrades option is unlocked after the player has destroyed Lableilara.
All bacteria upgrades are lost when attacking a planet or entering a Black Hole.
BPC Upgrades
Iterative BPC Upgrades
Iterative BPC upgrades can be purchased multiple times. Currently there is only one type of iterative BPC upgrade.
It is unlocked after obtaining 100 Bacteria guns and it can be purchased again after each 250 new Bacteria guns.
| Icon | Name | Effect | Prerequisite | Price (Bacteria) |
|---|---|---|---|---|
|
BPC upgrade | Increase your BPC by 50% | x100 Bacteria guns |  100
|
Regular BPC Upgrades
Regular BPC upgrades can be purchased only once per planet attack.
| Icon | Name | Effect | Prerequisite | Price (Bacteria) |
|---|---|---|---|---|
|
|
Bacteria gun upgrade | Bacteria gun 100% more powerful | x10 Bacteria guns | 2 500
|
| Bigger barrel | x25 Bacteria guns | 10 000
| ||
| Improved clip-size | x50 Bacteria guns | 50 000
| ||
| Spawner cooling system | x75 Bacteria guns | 250 000
| ||
| Improved reload speed | Bacteria gun 150% more powerful | x100 Bacteria guns | 1 000 000
| |
| New Bacteria gun model | Bacteria gun 200% more powerful | x125 Bacteria guns | 5 000 000
| |
| Upgrade to Bacteria mini-gun | Bacteria gun 250% more powerful | x150 Bacteria guns | 50 000 000
| |
| Petri empowered taps | Adds some Bacteria from BPS to BPC (1%) | x100 Petri dishes | 202 737
| |
|
Flask empowered Bacteria gun | Adds some Bacteria from BPS to BPC | x100 germ flasks | 2.03E+06
|
|
Trash based Bacteria gun upgrade | Adds some Bacteria from BPS to BPC | x100 trash bins | 2.55E+08
|
|
Compost based gun upgrade | Adds some Bacteria from BPS to BPC | x100 compost heaps | 5.36E+09
|
|
Radioactive gun upgrade | Adds some Bacteria from BPS to BPC | x100 nuclear reactors | 2.52E+21
|
|
Experimental gun technologies | Adds some Bacteria from BPS to BPC | x125 Area 52 | 5.00E+24
|
|
Space gun technologies | Adds some Bacteria from BPS to BPC | x100 space stations | 5.05E+26
|
|
Asteroid based gun upgrade | Adds some Bacteria from BPS to BPC | x100 industrialized asteroids | 4.15E+29
|
|
Planet based gun technologies | Adds some Bacteria from BPS to BPC | x150 artificial planets | 2.78E+33
|
|
Mars based gun technologies | Adds some Bacteria from BPS to BPC | x125 Mars colonies | 2.78E+43
|
|
Mercury based gun technologies | Adds some Bacteria from BPS to BPC | x125 Mercury colonies | 2.78E+51
|
|
Earth based gun technologies | Adds some Bacteria from BPS to BPC | x125 Earth colonies | 2.78E+59
|
|
Paflaolus based gun technologies | Adds some Bacteria from BPS to BPC | x125 Paflaolus colonies | 2.78E+69
|
|
Aclanus based gun technologies | Adds some Bacteria from BPS to BPC | x125 Aclanus colonies | 100
|
Colony Upgrades
| Icon | Name | Effect | Prerequisite | Price (Bacteria) | +BPS/+BPC | Iterative |
|---|---|---|---|---|---|---|
|
New Petri dish model 1 | Petri dish production +100% | x10 Petri dishes | 460
|
BPS | no |
| New Petri dish model 2 | x25 Petri dishes | 1 268
| ||||
| New Petri dish model 3 | x50 Petri dishes | 6 882
| ||||
| New Petri dish model 4 | Petri dish production +150% | x75 Petri dishes | 37 354
| |||
| Petri empowered taps | Adds some Bacteria from BPS to BPC (1%) | x100 Petri dishes | 202 737
|
BPC | ||
| Petri dish improvement | Petri dish production +200% | x200 Petri dishes | 100
|
BPS | yes | |
|
|
New flask model 1 | Flask production +100% | x10 germ flasks | 4.60E+03
|
BPS | no |
| New flask model 2 | x25 germ flasks | 1.27E+04
| ||||
| New flask model 3 | x50 germ flasks | 6.88E+04
| ||||
| New flask model 4 | Flask production +150% | x75 germ flasks | 3.74E+05
| |||
| Flask empowered Bacteria gun | Adds some Bacteria from BPS to BPC | x100 germ flasks | 2.03E+06
|
BPC | ||
| Flask improvement | Flask production +200% | x200 germ flasks | 100
|
BPS | yes | |
|
New Fish model 1 | Fish production +100% | x10 rotting fish | 4.14E+04
|
BPS | no |
| New Fish model 2 | x25 rotting fish | 1.14E+05
| ||||
| New Fish model 3 | x50 rotting fish | 6.19E+05
| ||||
| New Fish model 4 | Fish production +150% | x75 rotting fish | 3.36E+06
| |||
| Fish improvement | Fish production +200% | x200 rotting fish | 100
|
yes | ||
|
|
New trash bin model 1 | Trash bin production +100% | x10 trash bins | 5.79E+05
|
BPS | no |
| New trash bin model 2 | x25 trash bins | 1.60E+06
| ||||
| New trash bin model 3 | x50 trash bins | 8.67E+06
| ||||
| Trash based technology upgrade | All BPS +25% | x75 trash bins | 4.71E+07
| |||
| Trash based Bacteria gun upgrade | Adds some Bacteria from BPS to BPC | x100 trash bins | 2.55E+08
|
BPC | ||
| Trash bin improvement | Trash bin production +200% | x200 trash bins | 100
|
BPS | yes | |
|
|
Compost technology upgrade 1 | All BPS +20% | x10 compost heaps | 1.22E+07
|
BPS | no |
| Compost technology upgrade 2 | x25 compost heaps | 3.36E+07
| ||||
| Compost technology upgrade 3 | x50 compost heaps | 1.82E+08
| ||||
| Compost technology upgrade 4 | x75 compost heaps | 9.88E+08
| ||||
| Compost based gun upgrade | Adds some Bacteria from BPS to BPC | x100 compost heaps | 5.36E+09
|
BPC | ||
| Compost improvement | Compost production +200% | x200 compost heaps | 100
|
BPS | yes | |
|
Incubator upgrade 1 | Incubator production +100% | x10 incubators | 3.89E+08
|
BPS | no |
| Incubator upgrade 2 | x25 incubators | 1.07E+09
| ||||
| Incubator upgrade 3 | x50 incubators | 5.83E+09
| ||||
| Incubator upgrade 4 | Incubator production +150% | x75 incubators | 3.16E+10
| |||
| Incubator upgrade 5 | x100 incubators | 1.13E+11
| ||||
| Incubator improvement | Incubator production +200% | x200 incubators | 100
|
yes | ||
|
Farm upgrade 1 | Farm production +100% | x10 farms | 1.87E+10
|
BPS | no |
| Farm upgrade 2 | x25 farms | 5.15E+10
| ||||
| Farm upgrade 3 | x50 farms | 2.80E+11
| ||||
| Farm upgrade 4 | x75 farms | 1.52E+12
| ||||
| Farm based technology upgrade | All BPS +25% | x100 farms | 8.24E+12
| |||
| Farm improvement | Farm production +200% | x200 farms | 100
|
yes | ||
|
Laboratory upgrade 1 | Laboratory production +100% | x10 laboratories | 1.34E+12
|
BPS | no |
| Laboratory upgrade 2 | x25 laboratories | 3.71E+12
| ||||
| Laboratory upgrade 3 | x50 laboratories | 2.01E+13
| ||||
| Laboratory upgrade 4 | Laboratory production +150% | x75 laboratories | 1.09E+14
| |||
| Laboratory upgrade 5 | Laboratory production +400% | x100 laboratories | 8.26E+14
| |||
| Laboratory improvement | Laboratory production +200% | x200 laboratories | 100
|
yes | ||
|
Factory upgrade 1 | Factory production +100% | x10 factories | 1.45E+14
|
BPS | no |
| Factory upgrade 2 | x25 factories | 4.01E+14
| ||||
| Factory upgrade 3 | x50 factories | 2.18E+15
| ||||
| Factory upgrade 4 | Factory production +150% | x75 factories | 1.18E+16
| |||
| Factory upgrade 5 | Factory production +400% | x100 factories | 3.78E+17
| |||
| Factory improvement | Factory production +200% | x200 factories | 100
|
yes | ||
|
Sewage upgrade 1 | Sewage production +100% | x10 sewage networks | 2.35E+16
|
BPS | no |
| Sewage upgrade 2 | x25 sewage networks | 6.49E+16
| ||||
| Sewage upgrade 3 | x50 sewage networks | 3.52E+17
| ||||
| Sewage upgrade 4 | Sewage production +150% | x75 sewage networks | 1.91E+18
| |||
| Sewage upgrade 5 | Sewage production +400% | x100 sewage networks | 9.21E+18
| |||
| Sewage upgrade 6 | Sewage production +1000% | x125 sewage networks | 9.21E+18
| |||
| Sewage upgrade 7 | Sewage production +500% | x150 sewage networks | 9.21E+20
| |||
| Sewage improvement | Sewage production +200% | x200 sewage networks | 100
|
yes | ||
|
|
Reactor upgrade 1 | Reactor production +100% | x10 nuclear reactors | 5.72E+18
|
BPS | no |
| Reactor upgrade 2 | x25 nuclear reactors | 1.58E+19
| ||||
| Reactor upgrade 3 | x50 nuclear reactors | 8.56E+19
| ||||
| Reactor upgrade 4 | Reactor production +150% | x75 nuclear reactors | 4.65E+20
| |||
| Radioactive gun upgrade | Adds some Bacteria from BPS to BPC | x100 nuclear reactors | 2.52E+21
|
BPC | ||
| Reactor improvement | Reactor production +200% | X200 nuclear reactors | 100
|
BPS | yes | |
|
|
Area 52 upgrade 1 | All BPS +25% | x10 Area 52 | 2.09E+21
|
BPS | no |
| Area 52 upgrade 2 | x25 Area 52 | 5.76E+21
| ||||
| Area 52 upgrade 3 | x50 Area 52 | 3.13E+22
| ||||
| Area 52 upgrade 4 | x75 Area 52 | 1.70E+23
| ||||
| Area 52 upgrade 5 | All BPS +50% | X100 Area 52 | 9.21E+23
| |||
| Area 52 upgrade 6 | Area 52 production +10000% | X125 Area 52 | 5.41E+23
| |||
| Area 52 MEGA boost | Area 52 production +5000000% | X500 Area 52 | 5.41E+37
| |||
| Experimental gun technologies | Adds some Bacteria from BPS to BPC | x125 Area 52 | 5.00E+24
|
BPC | ||
| Area 52 improvement | Area 52 production +200% | X200 Area 52 | 100
|
BPS | yes | |
|
|
Space network | All BPS +25% | x10 space stations | 1.14E+24
|
BPS | no |
| Space station upgrade 2 | Space station production +100% | x25 space stations | 3.16E+24
| |||
| Space station upgrade 3 | x50 space stations | 1.71E+25
| ||||
| Space station upgrade 4 | Space station production +150% | x75 space stations | 9.30E+25
| |||
| Space station upgrade 5 | Space station production +300% | x125 space stations | 8.31E+27
| |||
| Space station upgrade 6 | Space station production +500% | x150 space stations | 6.20E+29
| |||
| Space station upgrade 7 | Space station production +1000% | x175 space stations | 2.30E+31
| |||
| Space gun technologies | Adds some Bacteria from BPS to BPC | x100 space stations | 5.05E+26
|
BPC | ||
| Space station improvement | Space station production +200% | x200 space stations | 100
|
BPS | yes | |
|
|
Asteroid upgrade 1 | Asteroid production +100% | x10 industrialized asteroids | 9.40E+26
|
BPS | no |
| Asteroid upgrade 2 | x25 industrialized asteroids | 2.59E+27
| ||||
| Asteroid upgrade 3 | x50 industrialized asteroids | 1.41E+28
| ||||
| Asteroid upgrade 4 | Asteroid production +150% | x75 industrialized asteroids | 7.64E+28
| |||
| Asteroid upgrade 5 | Asteroid production +1250% | x125 industrialized asteroids | 7.64E+29
| |||
| Asteroid upgrade 6 | Asteroid production +1250% | x175 industrialized asteroids | 7.64E+30
| |||
| Asteroid based gun upgrade | Adds some Bacteria from BPS to BPC | x100 industrialized asteroids | 4.15E+29
|
BPC | ||
| Asteroid improvement | Asteroid production +200% | x200 industrialized asteroids | 100
|
BPS | yes | |
|
|
Planet upgrade 1 | Planet production +100% | x10 artificial planets | 1.16E+30
|
BPS | no |
| Planet upgrade 2 | x25 artificial planets | 3.20E+30
| ||||
| Planet upgrade 3 | x50 artificial planets | 1.74E+31
| ||||
| Planet upgrade 4 | Planet production +150% | x75 artificial planets | 9.42E+31
| |||
| Planet upgrade 5 | x100 artificial planets | 5.11E+32
| ||||
| Planet upgrade 6 | Planet production +1500% | x125 artificial planets | 6.11E+33
| |||
| Planet upgrade 7 | Planet production +1500% | x175 artificial planets | 6.11E+35
| |||
| Planet based gun technologies | Adds some Bacteria from BPS to BPC | x150 artificial planets | 2.78E+33
|
BPC | ||
| Planet improvement | Planet production +200% | x200 artificial planets | 100
|
BPS | yes |
Colonized Planet Upgrades
| Icon | Name | Effect | Prerequisite | Price (Bacteria) | +BPS/+BPC | Iterative |
|---|---|---|---|---|---|---|
|
|
Mars upgrade 1 | Mars colony production +100% | x10 Mars colonies | 1.16E+40
|
BPS | no |
| Mars upgrade 2 | x25 Mars colonies | 3.20E+40
|
BPS | |||
| Mars upgrade 3 | x50 Mars colonies | 1.74E+41
|
BPS | |||
| Mars upgrade 4 | Mars colony production +150% | x75 Mars colonies | 9.42E+41
|
BPS | ||
| Mars upgrade 5 | x100 Mars colonies | 5.11E+42
|
BPS | |||
| Mars based gun technologies | Adds some Bacteria from BPS to BPC | x125 Mars colonies | 2.78E+43
|
BPC | ||
| Mars improvement | Mars colony production +200% | x200 Mars colonies | 100
|
BPS | yes | |
|
|
Mercury upgrade 1 | Mercury colony production +100% | x10 Mercury colonies | 1.16E+48
|
BPS | no |
| Mercury upgrade 2 | x25 Mercury colonies | 3.20E+48
|
BPS | |||
| Mercury upgrade 3 | x50 Mercury colonies | 1.74E+49
|
BPS | |||
| Mercury upgrade 4 | Mercury colony production +150% | x75 Mercury colonies | 9.42E+49
|
BPS | ||
| Mercury upgrade 5 | x100 Mercury colonies | 5.11E+50
|
BPS | |||
| Mercury based gun technologies | Adds some Bacteria from BPS to BPC | x125 Mercury colonies | 2.78E+51
|
BPC | ||
| Mercury improvement | Mercury colony production +200% | x200 Mercury colonies | 100
|
BPS | yes | |
|
|
Earth upgrade 1 | Earth colony production +100% | x10 Earth colonies | 1.16E+56
|
BPS | no |
| Earth upgrade 2 | x25 Earth colonies | 3.20E+56
|
BPS | |||
| Earth upgrade 3 | x50 Earth colonies | 1.74E+57
|
BPS | |||
| Earth upgrade 4 | Earth colony production +150% | x75 Earth colonies | 9.42E+57
|
BPS | ||
| Earth upgrade 5 | x100 Earth colonies | 5.11E+58
|
BPS | |||
| Earth based gun technologies | Adds some Bacteria from BPS to BPC | x125 Earth colonies | 2.78E+59
|
BPC | ||
| Earth improvement | Earth colony production +200% | x200 Earth colonies | 100
|
BPS | yes | |
|
|
Paflaolus upgrade 1 | Paflaolus colony production +100% | x10 Paflaolus colonies | 1.16E+66
|
BPS | no |
| Paflaolus upgrade 2 | x25 Paflaolus colonies | 3.20E+66
|
BPS | |||
| Paflaolus upgrade 3 | x50 Paflaolus colonies | 1.74E+67
|
BPS | |||
| Paflaolus upgrade 4 | Paflaolus colony production +150% | x75 Paflaolus colonies | 9.42E+67
|
BPS | ||
| Paflaolus upgrade 5 | x100 Paflaolus colonies | 5.11E+68
|
BPS | |||
| Paflaolus based gun technologies | Adds some Bacteria from BPS to BPC | x125 Paflaolus colonies | 2.78E+69
|
BPC | ||
| Paflaolus improvement | Paflaolus colony production +200% | x200 Paflaolus colonies | 100
|
BPS | yes | |
|
|
Aclanus upgrade 1 | Aclanus colony production +100% | x10 Aclanus colonies | 1.16E+79
|
BPS | no |
| Aclanus upgrade 2 | x25 Aclanus colonies | 3.20E+79
|
BPS | |||
| Aclanus upgrade 3 | x50 Aclanus colonies | 1.74E+80
|
BPS | |||
| Aclanus upgrade 4 | Aclanus colony production +150% | x75 Aclanus colonies | 9.42E+80
|
BPS | ||
| Aclanus upgrade 5 | x100 Aclanus colonies | 5.11E+81
|
BPS | |||
| Aclanus based gun technologies | Adds some Bacteria from BPS to BPC | x125 Aclanus colonies | 2.78E+82
|
BPC | ||
| Aclanus improvement | Aclanus colony production +200% | x200 Aclanus colonies | 100
|
BPS | yes | |
|
Lableilara upgrade 1 | Lableilara colony production +100% | x10 Lableilara colonies | 1.16E+96
|
BPS | no |
| Lableilara upgrade 2 | x25 Lableilara colonies | 3.20E+97
|
BPS | |||
| Lableilara upgrade 3 | x50 Lableilara colonies | 5.74E+97
|
BPS | |||
| Lableilara upgrade 4 | Lableilara colony production +150% | x75 Lableilara colonies | 6.42E+98
|
BPS | ||
| Lableilara upgrade 5 | x100 Lableilara colonies | 9.11E+100
|
BPS | |||
| Lableilara improvement | Lableilara colony production +200% | x200 Lableilara colonies | 100
|
BPS | yes | |
|
Atreria upgrade 1 | Atreria colony production +100% | x10 Atreria colonies | 1.16E+113
|
BPS | no |
| Atreria upgrade 2 | Atreria colony production +100% | x25 Atreria colonies | 1.20E+114
|
BPS | ||
| Atreria upgrade 3 | Atreria colony production +100% | x50 Atreria colonies | 5.74E+114
|
BPS | ||
| Atreria upgrade 4 | Atreria colony production +150% | x75 Atreria colonies | 2.82E+115
|
BPS | ||
| Atreria upgrade 5 | Atreria colony production +150% | x100 Atreria colonies | 5.26E+117
|
BPS | ||
| Atreria improvement | Atreria colony production +200% | x200 Atreria colonies | 100
|
BPS |
Gene Strand Upgrades
Gene Strand upgrades enable and increase the idle BPS bonus, tapping combo bonus, as well as provide various multipliers to total BPC and increase the production of different colonies.
New Gene Strand upgrades are unlocked by destroying planets. Previously purchased upgrades can be sold for 2/3 of their original Price (Gene Strands), rounded down.
Gene Strand upgrades remain after planet attacks, but are lost upon entering a Black Hole.
Gene Strand Bonus vs. Gene Strand Upgrades
The increase to Bacteria production from Gene Strand upgrades isn't always as big as the bonus from unspent Gene Strands.
The usefulness of Gene Strand upgrades usually differs depending on your playstyle and current progress in the game. For example, most upgrades to colony production are worth the Gene Strand investment only if most of Bacteria production comes from these colonies. Similarly, BPC and tapping combo upgrades are worth it only for an active tapping playstyle.
One of the exceptions to this rule are the Gene Strand upgrades that increase idle BPS bonus. These upgrades almost always increase your total BPS significantly.
This is because idle BPS also provides bonus to production when the game is closed and it will be active most of the time. Furthermore, idle BPS multiplies the bonus from the unspent Gene Strands, which means that the upgrade can be worth the cost even if the price of the upgrade is very high.
Example: Gene Strand Bonus vs. A.I. controlled production
A.I controlled production is an upgrade that costs 
2500 and increases the player's idle BPS bonus by 100%.
Let's say your BPS without any bonuses is 100.
If you have
100
(coefficient is
2.0),
your total BPS without the upgrade would be
100 × 2 × 1 = 200.
If you purchased the upgrade it would be
100 × 1 × 1.75 = 175.
As you can see, the BPS is now smaller.
If instead, you have 1000
(coefficient is 11.0), your total BPS without the upgrade would be
100 × 11 × 1 = 1100.
If you purchased the upgrade it would be
100 × 10 × 1.75 = 1750.
In this case, the total BPS has increased.
Upgrades Adding Bacteria from BPS to BPC
Some regular and Gene Strand upgrades increase BPC by a percentage of your total BPS. They do not decrease your total BPS.
The effectiveness of these upgrades is determined by:
- their base effect; and
- the number of destroyed planets.
The base effect is not displayed in the upgrade description. For regular upgrades, the base effect usually is 1%, but Toxic bullets, for example, has a base effect of 5%.
The final effect of the particular upgrade is calculated according to the formula:
effect = base effect / PlanetsDestroyed2